Pontresina is within easy reach from northern Switzerland, Ticino, Italy and Austria on safe, well-maintained alpine roads. In winter the valley is accessible over the Maloja, Julier, Ofen or Bernina passes.
| (in km) | (in hrs) | |
| City | Distance | Car |
| Zurich | 200 | 2.30 |
| Basel | 290 | 3.30 |
| St. Gallen | 190 | 2.30 |
| Geneva | 480 | 6.00 |
| Lugano | 125 | 2.30 |
| Milan | 175 | 2.30 |
| Florence | 470 | 5.30 |
| Munich | 300 | 4.00 |
| Stuttgart | 390 | 4.30 |
| Frankfurt | 590 | 6.00 |
| Innsbruck | 190 | 2.30 |
| Salzburg | 370 | 4.00 |
| Paris | 860 | 9.00 |